Prior information notice
This notice is for prior information only
Section I: Contracting
authority
I.1) Name and addresses
University Of Edinburgh
Charles Stewart House, 9-16 Chambers Street
Edinburgh
EH1 1HT
UK
Telephone: +44 1316502508
E-mail: esilves2@ed.ac.uk
NUTS: UKM75
Internet address(es)
Main address: https://www.ed.ac.uk
Address of the buyer profile: https://www.publiccontractsscotland.gov.uk/search/Search_AuthProfile.aspx?ID=AA00107
I.2) Joint procurement
The contract is awarded by a central purchasing body
I.3) Communication
Additional information can be obtained from the abovementioned address
I.4) Type of the contracting authority
Regional or local agency/office
I.5) Main activity
Education
Section II: Object
II.1) Scope of the procurement
II.1.1) Title
Single Cell Isolation Sorting and Dispensing system
Reference number: NCA31052
II.1.2) Main CPV code
42997300
II.1.3) Type of contract
Supplies
II.1.4) Short description
The University of Edinburgh is currently looking for market insight for a potential upcoming tender around robots having the capability to process single cells for mass spectrometry-based proteomics
The instrument has to be capable of isolating and lysing cells as well as automated protein digestion, peptide labelling with isotope tags and loading onto evotips. Instrument has to have the proven capability of reproducibly generating 100s of samples that can yield >1500 protein groups identified using a timsTOF SCP or similar mass spectrometer.
II.1.5) Estimated total value
Value excluding VAT:
290 000.00
GBP
II.1.6) Information about lots
This contract is divided into lots:
No
II.2) Description
II.2.2) Additional CPV code(s)
42997300
II.2.3) Place of performance
NUTS code:
UKM73
II.2.4) Description of the procurement
The IGC is a large multidisciplinary cross-college institute situated within the College of Medicine and Veterinary Medicine at the University of Edinburgh. IGC includes three world renowned research centres that advance knowledge and deliver basic science concepts to clinical and commercial outcomes within one world leading laboratory complex. The institute, together with its partner Deaneries and the College of Medicine and Veterinary Medicine provide a fertile and dynamic environment for medical research.
Over the past few years, we have witnessed a revolution in cellular and developmental biology. The advent of robust and sensitive mass spectrometry approaches has enabled us to quantify protein expression from single-cells (sc) Unbiased sc Proteomics has the potential to give us unprecedented insight into how cellular heterogeneity and changes within underpin most biological processes.
We have recently installed a timsTOF SCP coupled to an Evosep HPLC and have obtained funding from the BBSRC to purchase a robotic workstation for isolating, processing and labelling proteins/peptides isolated from single cells. The proposed instrument will enhance the capabilities and throughput of the University of Edinburgh to investigate the proteome at single cell resolution.
· The instrument must be capable of isolating and lysing cells as well as automated protein digestion, peptide labelling with isotope tags and loading onto evotips.
· The system must be able to introduce isotopic labels to permit multiplexing.
· Instrument has to have the proven capability of reproducibly generating 100s of samples that can yield >1500 protein groups identified using a timsTOF SCP or similar mass spectrometer.
The instrument will be unique to both the University of Edinburgh and to the surrounding areas. Our funders have asked that the instrument be available for the wider research community to access. Because of this we anticipate the system will be heavily used to mitigate against research being impacted by instrument downtime. We would require a system engineer to be available for onsite support and access to technical specialist support as required.
II.3) Estimated date of publication of contract notice:
30/10/2023
Section IV: Procedure
IV.1) Description
IV.1.8) Information about Government Procurement Agreement (GPA)
The procurement is covered by the Government Procurement Agreement:
Yes
Section VI: Complementary information
VI.3) Additional information
NOTE: To register your interest in this notice and obtain any additional information please visit the Public Contracts Scotland Web Site at https://www.publiccontractsscotland.gov.uk/Search/Search_Switch.aspx?ID=739929.
(SC Ref:739929)
VI.5) Date of dispatch of this notice
02/08/2023