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Contract Award Notice

Term Framework for the Provision of Chemistry Synthesis and other Chemistry Services Outsourcing Framework

  • First published: 01 December 2024
  • Last modified: 01 December 2024
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Contents

Summary

OCID:
ocds-h6vhtk-044ba4
Published by:
University of Dundee
Authority ID:
AA22823
Publication date:
01 December 2024
Deadline date:
-
Notice type:
Contract Award Notice
Has documents:
No
Has SPD:
No
Has Carbon Reduction Plan:
N/A

Abstract

Second-Generation Framework for the provision of Chemistry Synthesis and other Chemistry Services Outsourcing with initial term of two (2) years with the option to extend for up to 2 x 12 months, if required, at the sole discretion of the University and subject to ongoing satisfactory performance by the appointed Service Providers.

The Services will include:

1. FTE rate for provision of chemistry support for medicinal chemistry programme(s), typically making 50mg samples of compounds for initial biological evaluation. For actives, re-synthesis on a larger scale may be required (typically 0.5g to 5g scale). The ability to carry out array chemistry is important;

2.Bespoke piece(s) of chemistry e.g. synthesis of a defined list of compounds, typically at <50mg scale;

3. Scale up of chemistry, up to 200g;

4.Chiral separation by crystallization or SFC/Chiral HPLC on (up to) gram scale.

5.Synthesis of intermediates at 5-100g;

For all of these, a purity level will be defined. This will depend on the phase of the project, but typically is >95% purity and for scale up> 98% purity with no impurity >0.5%;

6. Experimental write-ups, when requested, including compound characterization by 1H NMR, 13C NMR and LCMS or UPLC/MS for publications, in-vivo release, tech-transfer to DDU or other CRO for patent purposes.

Full notice text

Contract award notice

Results of the procurement procedure

Section I: Contracting entity

I.1) Name and addresses

University of Dundee

Procurement, 3rd Floor, Tower Building, Nethergate

Dundee

DD1 4HN

UK

Contact person: Mary Kirkpatrick

Telephone: +44 1382386604

E-mail: m.y.kirkpatrick@dundee.ac.uk

NUTS: UKM71

Internet address(es)

Main address: http://www.dundee.ac.uk

Address of the buyer profile: https://www.publiccontractsscotland.gov.uk/search/Search_AuthProfile.aspx?ID=AA00105

I.2) Joint procurement

The contract is awarded by a central purchasing body

I.4) Type of the contracting authority

Body governed by public law

I.5) Main activity

Education

Section II: Object

II.1) Scope of the procurement

II.1.1) Title

Term Framework for the Provision of Chemistry Synthesis and other Chemistry Services Outsourcing Framework

Reference number: UoD-LAB031-TC-2023

II.1.2) Main CPV code

73110000

 

II.1.3) Type of contract

Services

II.1.4) Short description

Second-Generation Framework for the provision of Chemistry Synthesis and other Chemistry Services Outsourcing with initial term of two (2) years with the option to extend for up to 2 x 12 months, if required, at the sole discretion of the University and subject to ongoing satisfactory performance by the appointed Service Providers.

The Services will include:

1. FTE rate for provision of chemistry support for medicinal chemistry programme(s), typically making 50mg samples of compounds for initial biological evaluation. For actives, re-synthesis on a larger scale may be required (typically 0.5g to 5g scale). The ability to carry out array chemistry is important;

2.Bespoke piece(s) of chemistry e.g. synthesis of a defined list of compounds, typically at <50mg scale;

3. Scale up of chemistry, up to 200g;

4.Chiral separation by crystallization or SFC/Chiral HPLC on (up to) gram scale.

5.Synthesis of intermediates at 5-100g;

For all of these, a purity level will be defined. This will depend on the phase of the project, but typically is >95% purity and for scale up> 98% purity with no impurity >0.5%;

6. Experimental write-ups, when requested, including compound characterization by 1H NMR, 13C NMR and LCMS or UPLC/MS for publications, in-vivo release, tech-transfer to DDU or other CRO for patent purposes.

II.1.6) Information about lots

This contract is divided into lots: No

II.1.7) Total value of the procurement

Value excluding VAT: 1 000 000.00  GBP

II.2) Description

II.2.2) Additional CPV code(s)

73110000

II.2.3) Place of performance

NUTS code:

UKM71


Main site or place of performance:

Biological Chemistry & Drug Discovery (BCDD), University of Dundee

II.2.4) Description of the procurement

This Second-Generation Framework is required to provide a quick route to market for the provision of Chemistry Synthesis and other Chemistry Services. The initial contract term will be two (2) years, with the option to extend for 2 x 12 months, if required, at the sole discretion of BCDD and subject to ongoing satisfactory performance by the appointed Service Providers

The Chemistry Synthesis and Other Chemistry Services required will include:

1. FTE rate for provision of chemistry support for medicinal chemistry programme(s), typically making 50mg samples of compounds for initial biological evaluation. For actives, re-synthesis on a larger scale may be required (typically 0.5g to 5g scale). The ability to carry out array chemistry is important;

2. Bespoke piece(s) of chemistry e.g. synthesis of a defined list of compounds, typically at <50mg scale;

-Scale up of chemistry, up to 200g;

-Chiral separation by crystallization or SFC/Chiral HPLC on (up to) gram scale.

-Synthesis of intermediates at 5-100g;

For all of these, a purity level will be defined. This will depend on the phase of the project, but typically is >95% purity and for scale up> 98% purity with no impurity >0.5%;

-Experimental write-ups, when requested, including compound characterization by 1H NMR, 13C NMR and LCMS or UPLC/MS for publications, in-vivo release, tech-transfer to DDU or other CRO for patent purposes.

The subsequent route to market will be via Mini Comp under the Framework.

II.2.5) Award criteria

Quality criterion: 1. Account /Project Management & Communication / Weighting: 4

Quality criterion: 2.Range of Chemistry Synthesis and other Chemistry Services available. / Weighting: 10

Quality criterion: 3. Service Levels / Weighting: 10

Quality criterion: 4. Audit Control & Record Keeping / Weighting: 10

Quality criterion: 5. Sample CVs / Weighting: 2

Quality criterion: 6. Added Value / Weighting: 4

Price / Weighting:  60

II.2.11) Information about options

Options: No

II.2.13) Information about European Union funds

The procurement is related to a project and/or programme financed by European Union funds: No

Section IV: Procedure

IV.1) Description

IV.1.1) Type of procedure

Open procedure

IV.1.3) Information about a framework agreement or a dynamic purchasing system

The procurement involves the establishment of a framework agreement

IV.1.8) Information about Government Procurement Agreement (GPA)

The procurement is covered by the Government Procurement Agreement: Yes

IV.2) Administrative information

IV.2.1) Previous publication concerning this procedure

Notice number in the OJ S:

2024/S 000-009350

Section V: Award of contract

Contract No: UoD-LAB031-TC-2023

A contract/lot is awarded: Yes

V.2 Award of contract

V.2.1) Date of conclusion of the contract

22/07/2024

V.2.2) Information about tenders

Number of tenders received: 11

Number of tenders received from SMEs: 4

Number of tenders received from tenderers from EU Member States: 2

Number of tenders received from tenderers from non-EU Member States: 9

Number of tenders received by electronic means: 11

The contract has been awarded to a group of economic operators: Yes

V.2.3) Name and address of the contractor

TCG Lifesciences

Block BN, Plot 7, Saltlake Electronics Complex, Sector V

Kolkata, West Bengal, India

700091

(Country) Other

Telephone: +001 9194142706

NUTS: 1A

The contractor is an SME: No

V.2.3) Name and address of the contractor

3xper Innoventure Limited

Ticel Bio Park (Phase-2), 7th floor, Taramani

Chennai, Tamil Nadu

600113

IN

Telephone: +91 4440037721

NUTS: IN

The contractor is an SME: No

V.2.3) Name and address of the contractor

SYNGENE INTERNATIONAL LIMITED

BIOCON SPECIAL ECONOMIC ZONE, BIOCON PARK, PLOT NO. 2 & 3, IV PHASE, BOMMASANDRA INDUSTRIAL AREA,BOMMASANDRA-JIGANI LINK ROAD

BANGALORE

560099

IN

Telephone: +44 7414206297

E-mail: nan.zhao@syngeneintl.com

NUTS: IN

The contractor is an SME: No

V.2.3) Name and address of the contractor

BioAscent Discovery Ltd

Bo'ness rd

Newhouse

ML1 5UH

UK

Telephone: +44 1698534002

E-mail: asmith@bioascent.com

NUTS: UKM84

The contractor is an SME: No

V.2.3) Name and address of the contractor

Jubilant Biosys Limited

#96, Industrial Suburb, 2nd Stage, Yeshwanthpur

Bangalore

560022

IN

Telephone: +91 9886641533

NUTS: IN

The contractor is an SME: No

V.2.3) Name and address of the contractor

Cambridge Bioscience

Munro House

Cambridge

CB 23 8SQ

UK

Telephone: +44 1223316855

E-mail: hiten.patel@bioscience.co.uk

NUTS: UK

The contractor is an SME: No

V.2.3) Name and address of the contractor

Chemveda Life Sciences India Pvt. Ltd.

Plot- B 11/1, IDA Uppal

Hyderabad, Telangana

500039

IN

NUTS: IN

The contractor is an SME: No

V.2.3) Name and address of the contractor

Sai Life Sciences

Alderley Park

Macclesfield

SK104TG

UK

Telephone: +44 7789995203

E-mail: victoria.s@sailife.com

NUTS: UK

The contractor is an SME: No

V.2.3) Name and address of the contractor

"ENAMINE" SIA

Vestienas iela 2 B

Riga

LV-1035

LV

Telephone: +38 0444958814

NUTS: LV006

The contractor is an SME: No

V.2.3) Name and address of the contractor

ChemPartner Europe ApS

Ole Maaloes Vej 3,

Copenhagen

2200

DK

Telephone: +44 7768117764

NUTS: DK

The contractor is an SME: No

V.2.3) Name and address of the contractor

WuXi Apptec

5 New Street Square

London

EC4A 3TW

UK

Telephone: +44 1279777142

NUTS: UKI

The contractor is an SME: No

V.2.4) Information on value of the contract/lot (excluding VAT)

Initial estimated total value of the contract/lot:

Total value of the contract/lot: : 400 000.00  GBP

V.2.5) Information about subcontracting

Section VI: Complementary information

VI.3) Additional information

(SC Ref:784022)

VI.4) Procedures for review

VI.4.1) Review body

Dundee Sheriff Court

West Bell Street

Dundee

DD1 1HN

UK

VI.4.2) Body responsible for mediation procedures

Dundee Sheriff Court

West Bell Street

Dundee

DD1 4HN

UK

VI.5) Date of dispatch of this notice

26/11/2024

Coding

Commodity categories

ID Title Parent category
73110000 Research services Research and experimental development services

Delivery locations

ID Description
100 UK - All

Alert region restrictions

The buyer has restricted the alert for this notice to suppliers based in the following regions.

ID Description
There are no alert restrictions for this notice.

About the buyer

Main contact:
m.y.kirkpatrick@dundee.ac.uk
Admin contact:
N/a
Technical contact:
N/a
Other contact:
N/a

Further information

Date Details
No further information has been uploaded.

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