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Prior Information Notice

Market Engagement for Onasemnogene Abeparvovec (Zolgensma®) Service & Onasemnogene Abeparvovec Intrathecal (OAV101 IT) Service

  • First published: 09 January 2026
  • Last modified: 09 January 2026
  • Version: N/A
  • Record interest

     

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To record your interest or obtain additional information or documents please find instructions within the Full Notice Text. (NOTE: Contract Award Notices and Prior Information Notices do not normally require a response)

Contents

Summary

OCID:
Published by:
NHS England
Authority ID:
AA20005
Publication date:
09 January 2026
Deadline date:
-
Notice type:
Prior Information Notice
Has documents:
No
Has SPD:
No
Has Carbon Reduction Plan:
N/A

Abstract

The key objective of the Market Engagement Exercise is to seek feedback from the market regarding levels of interest, capability and capacity in relation to delivering the onasemnogene abeparvovec (zolgensma®) service and the onasemnogene abeparvovec intrathecal (OAV101 IT) service

Full notice text

Prior information notice

This notice aims at reducing time limits for receipt of tenders

Section I: Contracting authority

I.1) Name and addresses

NHS England

Wellington House, 133-135 Waterloo Rd

London

SE1 8UG

UK

Contact person: Surinder Kahlon

E-mail: surinder.kahlon@nhs.net

NUTS: UKJ1

Internet address(es)

Main address: https://www.england.nhs.uk/

Address of the buyer profile: https://www.england.nhs.uk/

I.3) Communication

The procurement documents are available for unrestricted and full direct access, free of charge at:

https://atamis-1928.my.site.com/s/Welcome


Additional information can be obtained from the abovementioned address


Tenders or requests to participate must be sent electronically to:

https://atamis-1928.my.site.com/s/Welcome


Tenders or requests to participate must be sent to the abovementioned address


Electronic communication requires the use of tools and devices that are not generally available. Unrestricted and full direct access to these tools and devices is possible, free of charge, at:

https://atamis-1928.my.site.com/s/Welcome


I.4) Type of the contracting authority

Body governed by public law

I.5) Main activity

Health

Section II: Object

II.1) Scope of the procurement

II.1.1) Title

Market Engagement for Onasemnogene Abeparvovec (Zolgensma®) Service & Onasemnogene Abeparvovec Intrathecal (OAV101 IT) Service

Reference number: C410884

II.1.2) Main CPV code

85100000

 

II.1.3) Type of contract

Services

II.1.4) Short description

The key objective of the Market Engagement Exercise is to seek feedback from the market regarding levels of interest, capability and capacity in relation to delivering the onasemnogene abeparvovec (zolgensma®) service and the onasemnogene abeparvovec intrathecal (OAV101 IT) service

II.1.5) Estimated total value

Value excluding VAT: .01  GBP

II.1.6) Information about lots

This contract is divided into lots: No

II.2) Description

II.2.3) Place of performance

NUTS code:

UK

II.2.4) Description of the procurement

The key objective of the Market Engagement Exercise is to seek feedback from the market regarding levels of interest, capability and capacity in relation to delivering the onasemnogene abeparvovec (zolgensma®) service and the onasemnogene abeparvovec intrathecal (OAV101 IT) service.<br/><br/>The commissioner isinterested in receiving feedback from the market on their capability and capacity to deliver services for zolgensma® or combined (zolgensma® and OAV101 IT).<br/><br/>It is also anticipated that the findings from this market engagement exercise will assist in the decision-making for the approach to commissioning the Service(s).<br/><br/>If, as a result of the market engagement, competition is absent or minimal, in any of the potential Lots/Regions, the Commissioner may use the Most Suitable Provider Process or Direct Award Process C. Where competition is absent, Direct Award Process A may be utilised. If, as a result of the market engagement, competition is apparent in a potential Lot/Region , a Competitive Process may be undertaken to award the contract for that Lot.<br/><br/>Service Summary:<br/>Spinal muscular atrophy, or SMA, is a rare genetic disorder that causes muscle weakness and progressive loss of movement. The severity of SMA can vary greatly between individuals. Historically, the condition has been classified into different types, determined by clinicians at the time of diagnosis. This classification is based on both the age at which symptoms first appear, and the highest level of motor function achieved by the patient. <br/><br/>The types range from type 0, the most severe form, where symptoms are present before birth and most affected infants don’t survive past 6 months, through to type 4, which develops in adulthood and is associated with mild motor impairment and a normal life span. However, because the disease presents so variably, consistently categorising patients into these types at the point of diagnosis can be challenging.<br/>Onasemnogene abeparvovec (zolgensma®) is a single-use gene replacement therapy made of a viral vector that has been modified to contain the primary gene for the human survival motor neuron (SMN) protein, which is lacking or mutated in people with SMA. When injected, the vector is expected to carry the gene into the nerve cells, enabling production of sufficient amounts of SMN. It is administered intravenously.<br/><br/>Onasemnogene abeparvovec intrathecal (OAV101 IT) is a one-time gene therapy for patients with SMA, proposed to treat people with SMA aged 2 years and over. This intrathecal injection will be used to treat a distinct population from the indication for Zolgensma®. <br/><br/>Following market engagement and review of capable providers, the Commissioner will consider the most appropriate PSR process(es) to formally commission each service. Interested parties may respond to this Market Engagement Exercise in partnership with other organisations as part of a consortium, subject to them appointing a consortium lead to act on their behalf as the lead contracting party would take overall responsibility for delivery of the service(s) in accordance with the requirements of any future contract(s) if successful.<br/><br/>To express interest and participate in the Market Engagement Exercise, please register and apply via Atamis esourcing portal https://health-family.force.com/s/Welcome <br/>Should Tenderers have any queries, or problems using the portal, they should contact the Helpdesk at:<br/>Phone: 08000988201<br/>E-mail: support-health@atamis.co.uk<br/>The closing date for completed Market Engagement responses is 12:00pm (noon), on Monday 2nd February 2026.<br/>Atamis Project reference C410884.

II.2.5) Award criteria

Criteria below:

Price

II.2.7) Duration of the contract, framework agreement or dynamic purchasing system

Duration in months: 108

II.2.13) Information about European Union funds

The procurement is related to a project and/or programme financed by European Union funds: No

II.3) Estimated date of publication of contract notice:

12/03/2026

Section IV: Procedure

IV.1) Description

IV.1.8) Information about Government Procurement Agreement (GPA)

The procurement is covered by the Government Procurement Agreement: Yes

Section VI: Complementary information

VI.4) Procedures for review

VI.4.1) Review body

NHS Arden and Greater East Midlands Commissioning Support Unit

Cardinal Square, 10 Nottingham Road

Derby

DE1 3QT

UK

Internet address(es)

URL: https://www.ardengemcsu.nhs.uk/

VI.5) Date of dispatch of this notice

08/01/2026

Coding

Commodity categories

ID Title Parent category
85100000 Health services Health and social work services

Delivery locations

ID Description
100 UK - All

Alert region restrictions

The buyer has restricted the alert for this notice to suppliers based in the following regions.

ID Description
There are no alert restrictions for this notice.

About the buyer

Main contact:
surinder.kahlon@nhs.net
Admin contact:
N/a
Technical contact:
N/a
Other contact:
N/a

Further information

Date Details
No further information has been uploaded.

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