II.2.3) Place of performance
NUTS code:
UKM75
Main site or place of performance:
The Queen's Medical Research Institute
II.2.4) Description of the procurement
This PIN refers to the purchase of a functional ultrasound (fUS) scanner (not to be confused with FUS which is focussed ultrasound – which is used for ultrasound therapy applications such as ablation).
Essential Scanner Features
Non-invasive brain imaging: Imaging of brain blood flow dynamics in the mouse brain without the need to create an acoustic window
High spatial resolution: Ability to achieve real-time spatial resolution better than 100 microns sufficient for visualising the mouse brain
High temporal resolution: Ability to achieve temporal resolution better than 100 ms to enable dynamic imaging of brain blood flow
Atlas registration: In-built Allen brain atlas so that the acquired brain images can be registered
Functional connectivity analysis: In-built interactive software to build connectivity matrices, seed maps, and perform region-based analyses.
Ultrasound localisation microscopy: Capability for super-resolution imaging and visualisation of the microvascular tree in the brain or other soft tissue organs, including associated analysis software.
3D imaging support: Ability to perform volumetric imaging and reconstruction of brain regions.
Blood flow velocity analysis: Software to support calculation of the velocity of blood moving within the micro- vasculature of the brain or other soft tissue organs
Portability and motorised scanning: Portable/moveable system with motorised scanning table and associated hardware to support ultrasound scanning of fixed-head or fixed-organ animals.
Offline analysis: Full capability for offline data analysis, including export to standard analysis platforms (e.g. MATLAB, Python).
Awake and anaesthetised imaging: System adaptable for both anaesthetised and awake mouse imaging, including head-fixation and behavioural setups.
Physiological synchronisation: Compatibility with physiological monitoring systems (e.g. ECG, respiration) and synchronisation with external equipment such as stimulation, electrophysiology, or behavioural tracking systems.
Upgrade and expandability: Modular design to support future hardware or software upgrades (e.g. dual-probe imaging, extended field-of-view).
Training and technical support: Comprehensive technical support, including on-site installation, user training, software updates, and a warranty/maintenance plan.