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Lot No: 1
II.2.1) Title
DNA Sequencing Services
II.2.2) Additional CPV code(s)
73110000
73111000
II.2.3) Place of performance
NUTS code:
UK
II.2.4) Description of the procurement
UK SBS wish to put in place a framework for the purchase a range of user selectable DNA Sequencing services (Sanger/ ~800-1000 base pair read) from a range of samples and formats including tubes, microtiter plates, preparation & extractions services including from colonies and tissue, with the capability of sequencing from High GC and AT samples.
II.2.5) Award criteria
Price is not the only award criterion and all criteria are stated only in the procurement documents
II.2.7) Duration of the contract, framework agreement or dynamic purchasing system
Duration in months: 24
This contract is subject to renewal: Yes
Description of renewals:
This Contract is being Let on a 2 year + 1 Year + 1 Year basis
II.2.9) Information about the limits on the number of candidates to be invited
II.2.10) Information about variants
Variants will be accepted:
No
II.2.11) Information about options
Options:
No
II.2.13) Information about European Union funds
The procurement is related to a project and/or programme financed by European Union funds:
No
II.2.14) Additional information
The number of envisaged suppliers for this Lot is 10
Lot No: 2.1
II.2.1) Title
Sub Lot 2.1 Custom gene fragment synthesis (less than 2000 base pairs)
II.2.2) Additional CPV code(s)
73110000
73111000
II.2.3) Place of performance
NUTS code:
UK
II.2.4) Description of the procurement
UK SBS wish to put in place a framework for the purchase a range of user selectable (via supplier engagement) range of Custom Gene Synthesis.
Custom Gene fragment synthesis (sub 2000 base pairs)
For the above sub-lot, a range of user selectable additional services should be available (but are not mandatory). This could include but is not limited to the following:
• Genes produced with additional synthetic Nucleotides (AGTC + XY)
• Custom vector production
• Codon optimized sequences – all species
• Site-directed mutagenesis
• Bacterial, yeast, Baculovirus and mammalian gene expression services
• Complex sequence synthesis - GC rich, AT rich, complex repeats & hairpin structures and toxic sequences
II.2.5) Award criteria
Price is not the only award criterion and all criteria are stated only in the procurement documents
II.2.7) Duration of the contract, framework agreement or dynamic purchasing system
Duration in months: 24
This contract is subject to renewal: Yes
Description of renewals:
This Contract is being Let on a 2 year + 1 Year + 1 Year basis
II.2.9) Information about the limits on the number of candidates to be invited
II.2.10) Information about variants
Variants will be accepted:
No
II.2.11) Information about options
Options:
No
II.2.13) Information about European Union funds
The procurement is related to a project and/or programme financed by European Union funds:
No
II.2.14) Additional information
The number of envisaged suppliers for this Lot is 10
Lot No: 2.2
II.2.1) Title
Sub Lot 2.2 Custom gene synthesis (2001-3000 base pairs)
II.2.2) Additional CPV code(s)
73110000
73111000
II.2.3) Place of performance
NUTS code:
UK
II.2.4) Description of the procurement
UK SBS wish to put in place a framework for the purchase a range of user selectable (via supplier engagement) range of Custom Gene Synthesis.
Custom Gene synthesis (2001 - 3000 base pairs)
For the above sub-lot, a range of user selectable additional services should be available (but are not mandatory). This could include but is not limited to the following:
• Genes produced with additional synthetic Nucleotides (AGTC + XY)
• Custom vector production
• Codon optimized sequences – all species
• Site-directed mutagenesis
• Bacterial, yeast, Baculovirus and mammalian gene expression services
• Complex sequence synthesis - GC rich, AT rich, complex repeats & hairpin structures and toxic sequences
II.2.5) Award criteria
Price is not the only award criterion and all criteria are stated only in the procurement documents
II.2.7) Duration of the contract, framework agreement or dynamic purchasing system
Duration in months: 24
This contract is subject to renewal: Yes
Description of renewals:
This Contract is being Let on a 2 year + 1 Year + 1 Year basis
II.2.9) Information about the limits on the number of candidates to be invited
II.2.10) Information about variants
Variants will be accepted:
No
II.2.11) Information about options
Options:
No
II.2.13) Information about European Union funds
The procurement is related to a project and/or programme financed by European Union funds:
No
II.2.14) Additional information
The number of envisaged suppliers for this Lot is 10
Lot No: 2.3
II.2.1) Title
Sub Lot 2.3 Custom Gene synthesis (3001-5000 base pairs)
II.2.2) Additional CPV code(s)
73110000
73111000
II.2.3) Place of performance
NUTS code:
UK
II.2.4) Description of the procurement
UK SBS wish to put in place a framework for the purchase a range of user selectable (via supplier engagement) range of Custom Gene Synthesis.
Custom Gene synthesis (3001-5000 base pairs)
For the above sub-lot, a range of user selectable additional services should be available (but are not mandatory). This could include but is not limited to the following:
• Genes produced with additional synthetic Nucleotides (AGTC + XY)
• Custom vector production
• Codon optimized sequences – all species
• Site-directed mutagenesis
• Bacterial, yeast, Baculovirus and mammalian gene expression services
• Complex sequence synthesis - GC rich, AT rich, complex repeats & hairpin structures and toxic sequences
II.2.5) Award criteria
Price is not the only award criterion and all criteria are stated only in the procurement documents
II.2.7) Duration of the contract, framework agreement or dynamic purchasing system
Duration in months: 24
This contract is subject to renewal: Yes
Description of renewals:
This Contract is being Let on a 2 year + 1 Year + 1 Year basis
II.2.9) Information about the limits on the number of candidates to be invited
II.2.10) Information about variants
Variants will be accepted:
No
II.2.11) Information about options
Options:
No
II.2.13) Information about European Union funds
The procurement is related to a project and/or programme financed by European Union funds:
No
II.2.14) Additional information
The number of envisaged suppliers for this Lot is 10
Lot No: 2.4
II.2.1) Title
Sub Lot 2.4 Custom Gene synthesis (5001+ bp)
II.2.2) Additional CPV code(s)
73110000
73111000
II.2.3) Place of performance
NUTS code:
UK
II.2.4) Description of the procurement
UK SBS wish to put in place a framework for the purchase a range of user selectable (via supplier engagement) range of Custom Gene Synthesis.
Custom Gene synthesis (5001+ bp)
For the above sub-lot, a range of user selectable additional services should be available (but are not mandatory). This could include but is not limited to the following:
• Genes produced with additional synthetic Nucleotides (AGTC + XY)
• Custom vector production
• Codon optimized sequences – all species
• Site-directed mutagenesis
• Bacterial, yeast, Baculovirus and mammalian gene expression services
• Complex sequence synthesis - GC rich, AT rich, complex repeats & hairpin structures and toxic sequences
II.2.5) Award criteria
Price is not the only award criterion and all criteria are stated only in the procurement documents
II.2.7) Duration of the contract, framework agreement or dynamic purchasing system
Duration in months: 24
This contract is subject to renewal: Yes
Description of renewals:
This Contract is being Let on a 2 year + 1 Year + 1 Year basis
II.2.9) Information about the limits on the number of candidates to be invited
II.2.10) Information about variants
Variants will be accepted:
No
II.2.11) Information about options
Options:
No
II.2.13) Information about European Union funds
The procurement is related to a project and/or programme financed by European Union funds:
No
II.2.14) Additional information
The number of envisaged suppliers for this Lot is 10
Lot No: 3.1
II.2.1) Title
Sub Lot 3.1 Gene Specific DNA Methylation
II.2.2) Additional CPV code(s)
73110000
73111000
II.2.3) Place of performance
NUTS code:
UK
II.2.4) Description of the procurement
UK SBS wish to put in place a framework for the purchase a range of Gene Specific DNA Methylation services are required to include,
But not limited to:
O Perform Bisulfite modification
O Perform PCR reactions
O Perform Pyrosequencing analysis
II.2.5) Award criteria
Price is not the only award criterion and all criteria are stated only in the procurement documents
II.2.7) Duration of the contract, framework agreement or dynamic purchasing system
Duration in months: 24
This contract is subject to renewal: Yes
Description of renewals:
This Contract is being Let on a 2 year + 1 Year + 1 Year basis
II.2.9) Information about the limits on the number of candidates to be invited
II.2.10) Information about variants
Variants will be accepted:
No
II.2.11) Information about options
Options:
No
II.2.13) Information about European Union funds
The procurement is related to a project and/or programme financed by European Union funds:
No
II.2.14) Additional information
The number of envisaged suppliers for this Lot is 10
Lot No: 3.2
II.2.1) Title
Sub Lot 3.2 Global DNA Methylation
II.2.2) Additional CPV code(s)
73110000
73111000
II.2.3) Place of performance
NUTS code:
UK
II.2.4) Description of the procurement
UK SBS wish to put in place a framework for the purchase Global DNA Methylation
A range of global DNA methylation services are required to include, but not limited to:
O LC MS DNA-methylation analysis
O ELISA that enables the direct quantitation of genomic DNA methylation.
O PCR based methods e.g. Alu and LINE1
O Methylation sensitive restriction assays eg luminometric methylation assay (LUMA).
II.2.5) Award criteria
Price is not the only award criterion and all criteria are stated only in the procurement documents
II.2.7) Duration of the contract, framework agreement or dynamic purchasing system
Duration in months: 24
This contract is subject to renewal: Yes
Description of renewals:
This Contract is being Let on a 2 year + 1 Year + 1 Year basis
II.2.9) Information about the limits on the number of candidates to be invited
II.2.10) Information about variants
Variants will be accepted:
No
II.2.11) Information about options
Options:
No
II.2.13) Information about European Union funds
The procurement is related to a project and/or programme financed by European Union funds:
No
II.2.14) Additional information
The number of envisaged suppliers for this Lot is 10
Lot No: 3.3
II.2.1) Title
Sub Lot 3.3 Allele quantification
II.2.2) Additional CPV code(s)
73110000
73111000
II.2.3) Place of performance
NUTS code:
UK
II.2.4) Description of the procurement
UK SBS wish to put in place a framework for the purchase Allele quantification
A range of Allele quantification services are required to include, but not limited to:
O SNP detection and quantification
O Assay development for SNP detection and quantification from pooled DNA with a defined 100bp target region in murine DNA
O Validation of the above assay
O Sample testing if required for the above assay.
II.2.5) Award criteria
Price is not the only award criterion and all criteria are stated only in the procurement documents
II.2.7) Duration of the contract, framework agreement or dynamic purchasing system
Duration in months: 24
This contract is subject to renewal: Yes
Description of renewals:
This Contract is being Let on a 2 year + 1 Year + 1 Year basis
II.2.9) Information about the limits on the number of candidates to be invited
II.2.10) Information about variants
Variants will be accepted:
No
II.2.11) Information about options
Options:
No
II.2.13) Information about European Union funds
The procurement is related to a project and/or programme financed by European Union funds:
No
II.2.14) Additional information
The number of envisaged suppliers for this Lot is 10
Lot No: 4.1
II.2.1) Title
Sub Lot 4.1 DNA olgonucleotides
II.2.2) Additional CPV code(s)
73110000
73111000
II.2.3) Place of performance
NUTS code:
UK
II.2.4) Description of the procurement
UK SBS wish to put in place a framework for the purchase of a range of custom Oligonucleotide synthesis services including Custom DNA oligo’s in tubes, plates and RNA/siRNA, to be user selectable via supplier engagement with a range of purification and modification options.
Synthesis of DNA oligonucleotides.
The production of custom user defined oligonucleotides in the following ranges are required (Inc. plates)
• 0.01UM bases standard
• 0.05UM bases standard
• 0.2UM bases standard
• 1.0UM bases standard
• 0.025 UM / 3OD
• Microtiter plates
II.2.5) Award criteria
Price is not the only award criterion and all criteria are stated only in the procurement documents
II.2.7) Duration of the contract, framework agreement or dynamic purchasing system
Duration in months: 24
This contract is subject to renewal: Yes
Description of renewals:
This Contract is being Let on a 2 year + 1 Year + 1 Year basis
II.2.9) Information about the limits on the number of candidates to be invited
II.2.10) Information about variants
Variants will be accepted:
No
II.2.11) Information about options
Options:
No
II.2.13) Information about European Union funds
The procurement is related to a project and/or programme financed by European Union funds:
No
II.2.14) Additional information
The number of envisaged suppliers for this Lot is 10
Lot No: 4.2
II.2.1) Title
Sub Lot 4.2 Custom RNA oligo’s
II.2.2) Additional CPV code(s)
73110000
73111000
II.2.3) Place of performance
NUTS code:
UK
II.2.4) Description of the procurement
UK SBS wish to put in place a framework for the purchase of a range of custom Oligonucleotide synthesis services including Custom DNA oligo’s in tubes, plates and RNA/siRNA, to be user selectable via supplier engagement with a range of purification and modification options.
Synthesis of Custom RNA oligo’s (both Single and double stranded RNA oligoes, siRNA) the supply of siRNA Libraries and the production of custom SiRNA Libraries
The production of custom user defined oligonucleotides in the following ranges are required (Inc. plates)
• 0.01UM bases standard
• 0.05UM bases standard
• 0.2UM bases standard
• 1.0UM bases standard
• 0.025 UM / 3OD
• Microtiter plates
II.2.5) Award criteria
Price is not the only award criterion and all criteria are stated only in the procurement documents
II.2.7) Duration of the contract, framework agreement or dynamic purchasing system
Duration in months: 24
This contract is subject to renewal: Yes
Description of renewals:
This Contract is being Let on a 2 year + 1 Year + 1 Year basis
II.2.9) Information about the limits on the number of candidates to be invited
II.2.10) Information about variants
Variants will be accepted:
No
II.2.11) Information about options
Options:
No
II.2.13) Information about European Union funds
The procurement is related to a project and/or programme financed by European Union funds:
No
II.2.14) Additional information
The number of envisaged suppliers for this Lot is 10
(i) not to award any contract as a result of the procurement process commenced by publication of this notice; and
(ii) to make whatever changes it may see fit to the content and structure of the procurement; and in no circumstances will the Contracting Authority be liable for any costs incurred by any Supplier.
If the Contracting authority decides to enter into a Contract with the successful supplier, this does not mean that there is any guarantee of subsequent contracts being awarded. Any expenditure, work or effort undertaken prior to contract award is accordingly a matter solely for the commercial judgement of Bidders. All submissions will be assessed in accordance with the Public Contracts Regulations 2015, for procurement values that exceed Regulation 5 (Threshold amounts). The sourcing documents can be accessed at: https://gpsesourcing.cabinetoffice.gov.uk using the instructions detailed in I.3. Deadline for request for participation is Thursday 29.11.2018 11:00 am. Deadline for receipt of Tenders is Friday 30.11.2018 14:00 pm.