Contract notice
Section I: Contracting
authority
I.1) Name and addresses
UNIVERSITY OF SHEFFIELD
RC000667
THE UNIVERSITY OF SHEFFIELD,WESTERN BANK
SHEFFIELD
S102TN
UK
Contact person: James Noble
E-mail: james.noble@sheffield.ac.uk
NUTS: UKE32
Internet address(es)
Main address: https://intendhost.co.uk/sheffield
I.3) Communication
The procurement documents are available for unrestricted and full direct access, free of charge at:
https://intendhost.co.uk/sheffield
Additional information can be obtained from the abovementioned address
Tenders or requests to participate must be sent electronically to:
https://intendhost.co.uk/sheffield
I.4) Type of the contracting authority
Body governed by public law
I.5) Main activity
Education
Section II: Object
II.1) Scope of the procurement
II.1.1) Title
3900/JN/23 - Design and construction of an automated and compact mRNA GMP manufacturing system
Reference number: 3900/JN/23
II.1.2) Main CPV code
73300000
II.1.3) Type of contract
Services
II.1.4) Short description
Zoltan Kis from the University of Sheffield's department of Chemical and Biological Engineering with funding from Innovate UK is seeking a supplier to collaborate on the creation of an automated and compact GMP manufacturing system. The provider will be responsible for the design and prototyping of a custom system in-order to support the group's drive towards GMP, automated RNA production.
II.1.5) Estimated total value
Value excluding VAT:
760 000.00
GBP
II.1.6) Information about lots
This contract is divided into lots:
No
II.2) Description
II.2.3) Place of performance
NUTS code:
UKE32
II.2.4) Description of the procurement
Zoltan Kis from the University of Sheffield's department of Chemical and Biological Engineering with funding from Innovate UK is seeking a supplier to collaborate on the creation of an automated and compact GMP manufacturing system. The provider will be responsible for the design and prototyping of a custom system in-order to support the group's drive towards GMP, automated RNA production.
The high-level work required is:
• The provider will work with The Kis Group to generate an engineering specification that meets their bioprocess. To achieve this the provider must have a working understanding of standard bioprocess techniques and have hands-on laboratory experience.
• The provider will generate high-level concepts to be discussed and reviewed by The Kis Group.
• The provider will then work with The Kis Group to allocate specific sections of work packages between the provider and The Kis Group.
• The provider will start by completing work packages that automate each of the individual RNA production steps (IVT, purification, LNP formation). For each of these work packages the provider will design concepts, review them with The Kis Group, generate manufacture files and source parts.
• The provider will assist The Kis Group in testing the sub-system prototypes in the biology lab. The provider must therefore have a team member with experience in biology labs.
• After subsystems are validated the provider will be responsible for designing a complete integrated system. Following concept design the provider will generate manufacturing documents and source components. The provider will work with The Kis Group to validate the integrated system against key bioprocess outputs.
II.2.5) Award criteria
Price is not the only award criterion and all criteria are stated only in the procurement documents
II.2.7) Duration of the contract, framework agreement or dynamic purchasing system
Duration in months: 24
This contract is subject to renewal: No
II.2.9) Information about the limits on the number of candidates to be invited
II.2.10) Information about variants
Variants will be accepted:
No
II.2.11) Information about options
Options:
No
II.2.13) Information about European Union funds
The procurement is related to a project and/or programme financed by European Union funds:
No
Section III: Legal, economic, financial and technical information
III.1) Conditions for participation
III.1.3) Technical and professional ability
Selection criteria as stated in the procurement documents
III.2) Conditions related to the contract
Section IV: Procedure
IV.1) Description
IV.1.1) Type of procedure
Open procedure
IV.1.8) Information about Government Procurement Agreement (GPA)
The procurement is covered by the Government Procurement Agreement:
Yes
IV.2) Administrative information
IV.2.2) Time limit for receipt of tenders or requests to participate
Date:
17/10/2023
Local time: 12:00
IV.2.4) Languages in which tenders or requests to participate may be submitted
EN
IV.2.6) Minimum time frame during which the tenderer must maintain the tender
Duration in months: 3 (from the date stated for receipt of tender)
IV.2.7) Conditions for opening of tenders
Date:
17/10/2023
Local time: 12:01
Section VI: Complementary information
VI.1) Information about recurrence
This is a recurrent procurement:
No
VI.2) Information about electronic workflows
Electronic ordering will be used
Electronic invoicing will be accepted
Electronic payment will be used
VI.4) Procedures for review
VI.4.1) Review body
University of Sheffield
Sheffield
S10 2TN
UK
E-mail: james.noble@sheffield.ac.uk
VI.5) Date of dispatch of this notice
15/09/2023