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02 Contract Notice

Drug Development Framework

  • First published: 15 April 2020
  • Last modified: 18 January 2021
  • Version: N/A
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Contents

Summary

OCID:
ocds-kuma6s-101107
Published by:
Cardiff University
Authority ID:
AA0258
Publication date:
15 April 2020
Deadline date:
17 January 2021
Notice type:
02 Contract Notice
Has documents:
No
Has SPD:
No
Has Carbon Reduction Plan:
N/A

Abstract

Cardiff University are ranked 2nd nationally for the impact of their research and are among the top five universities in the UK for research excellence. Cardiff University has a thriving and innovative research culture, with research that has real impact and makes a positive difference to the world. As part of this, the University is translating fundamental discoveries in disease processes to develop new medicines to meet unmet clinical needs. Cardiff University is looking for companies with an innovative outlook and recognised expertise in supporting drug-discovery projects from early screening (electrophysiology and in vitro DMPK) to delivering de-risked novel molecules to clinical trials. Successful companies will be committed to the principles of the NC3Rs and will add value to our work by providing high-quality data for informing the drug-discovery pipeline. CPV: 73111000, 73111000, 73111000, 73111000, 73111000.

Full notice text

Contract notice

Section I: Contracting authority

I.1) Name and addresses

Cardiff University

Procurement Services, McKenzie House, 30-36 Newport Road

Cardiff

CF24 0DE

UK

Telephone: +44 2920879648

E-mail: Buyline@cardiff.ac.uk

NUTS: UKL

Internet address(es)

Main address: http://www.cardiff.ac.uk/business/why-work-with-us/for-suppliers

Address of the buyer profile: https://www.sell2wales.gov.wales/search/Search_AuthProfile.aspx?ID=AA0258

I.3) Communication

The procurement documents are available for unrestricted and full direct access, free of charge at:

https://in-tendhost.co.uk/cardiffuniversity/aspx/Home


Additional information can be obtained from the abovementioned address


Tenders or requests to participate must be sent electronically to:

https://in-tendhost.co.uk/cardiffuniversity/aspx/Home


I.4) Type of the contracting authority

Body governed by public law

I.5) Main activity

Education

Section II: Object

II.1) Scope of the procurement

II.1.1) Title

Drug Development Framework

Reference number: CU258

II.1.2) Main CPV code

73111000

 

II.1.3) Type of contract

Services

II.1.4) Short description

Cardiff University are ranked 2nd nationally for the impact of their research and are among the top five universities in the UK for research excellence. Cardiff University has a thriving and innovative research culture, with research that has real impact and makes a positive difference to the world. As part of this, the University is translating fundamental discoveries in disease processes to develop new medicines to meet unmet clinical needs.

Cardiff University is looking for companies with an innovative outlook and recognised expertise in supporting drug-discovery projects from early screening (electrophysiology and in vitro DMPK) to delivering de-risked novel molecules to clinical trials. Successful companies will be committed to the principles of the NC3Rs and will add value to our work by providing high-quality data for informing the drug-discovery pipeline.

II.1.6) Information about lots

This contract is divided into lots: Yes

Tenders may be submitted for all lots

II.2) Description

Lot No: 1

II.2.1) Title

Electrophysiology Services

II.2.2) Additional CPV code(s)

73111000

II.2.3) Place of performance

NUTS code:

UKL22

II.2.4) Description of the procurement

We require providers for electrophysiology services relevant to neuroscience drug development.

Currently we require validated ion channel assays for GABAA and NMDA modulators, on an automated electrophysiology platform, with QC and report generation.

In the near future, it is likely we will require a range of other ion channel assays, as well as manual patch clamp services. We may also want to purchase ion channel expressing cell lines (under a MTA).

II.2.5) Award criteria

Price is not the only award criterion and all criteria are stated only in the procurement documents

II.2.7) Duration of the contract, framework agreement or dynamic purchasing system

Duration in months: 24

This contract is subject to renewal: Yes

Description of renewals:

This Framework shall run for an initial period of two years. Where appropriate, and subject to agreement, the Framework may be extended in one-year increments provided that the total life of the Framework does not exceed four years (2+1+1).

II.2.9) Information about the limits on the number of candidates to be invited

II.2.10) Information about variants

Variants will be accepted: No

II.2.11) Information about options

Options: No

II.2.13) Information about European Union funds

The procurement is related to a project and/or programme financed by European Union funds: Yes

Lot No: 2

II.2.1) Title

In-vivo assays

II.2.2) Additional CPV code(s)

73111000

II.2.3) Place of performance

NUTS code:

UKL22

II.2.4) Description of the procurement

We require providers for in-vivo assays, most usually with oral administration. We currently require reliable assays for pro-cognitive and anxiolytic effects. In the future, we may require assays to demonstrate other drug modulated effects, such as, but not limited to, an anti-depressive effect.

II.2.5) Award criteria

Price is not the only award criterion and all criteria are stated only in the procurement documents

II.2.7) Duration of the contract, framework agreement or dynamic purchasing system

Duration in months: 24

This contract is subject to renewal: Yes

Description of renewals:

This Framework shall run for an initial period of two years. Where appropriate, and subject to agreement, the Framework may be extended in one-year increments provided that the total life of the Framework does not exceed four years (2+1+1).

II.2.9) Information about the limits on the number of candidates to be invited

II.2.10) Information about variants

Variants will be accepted: No

II.2.11) Information about options

Options: No

II.2.13) Information about European Union funds

The procurement is related to a project and/or programme financed by European Union funds: Yes

Lot No: 3

II.2.1) Title

In-vitro drug metabolism (ADME-Tox) services

II.2.2) Additional CPV code(s)

73111000

II.2.3) Place of performance

NUTS code:

UKL22

II.2.4) Description of the procurement

We require providers of in-vitro drug metabolism (ADME-Tox) services as part of our drug development pipeline. This includes, but is not limited to, measures of metabolism, permeability and transporters, physicochemical properties, protein binding and toxicology.

II.2.5) Award criteria

Price is not the only award criterion and all criteria are stated only in the procurement documents

II.2.7) Duration of the contract, framework agreement or dynamic purchasing system

Duration in months: 24

This contract is subject to renewal: Yes

Description of renewals:

This Framework shall run for an initial period of two years. Where appropriate, and subject to agreement, the Framework may be extended in one-year increments provided that the total life of the Framework does not exceed four years (2+1+1).

II.2.9) Information about the limits on the number of candidates to be invited

II.2.10) Information about variants

Variants will be accepted: No

II.2.11) Information about options

Options: No

II.2.13) Information about European Union funds

The procurement is related to a project and/or programme financed by European Union funds: Yes

Lot No: 4

II.2.1) Title

In-vivo pharmacokinetics (PK) and toxicology

II.2.2) Additional CPV code(s)

73111000

II.2.3) Place of performance

NUTS code:

UKL22

II.2.4) Description of the procurement

We require providers of in-vivo drug metabolism (ADME-Tox) services as part of our drug development pipeline.

II.2.5) Award criteria

Price is not the only award criterion and all criteria are stated only in the procurement documents

II.2.7) Duration of the contract, framework agreement or dynamic purchasing system

Duration in months: 24

This contract is subject to renewal: Yes

Description of renewals:

This Framework shall run for an initial period of two years. Where appropriate, and subject to agreement, the Framework may be extended in one-year increments provided that the total life of the Framework does not exceed four years (2+1+1).

II.2.9) Information about the limits on the number of candidates to be invited

II.2.10) Information about variants

Variants will be accepted: No

II.2.11) Information about options

Options: No

II.2.13) Information about European Union funds

The procurement is related to a project and/or programme financed by European Union funds: Yes

Section III: Legal, economic, financial and technical information

III.1) Conditions for participation

III.1.2) Economic and financial standing

Selection criteria as stated in the procurement documents


III.1.3) Technical and professional ability

Selection criteria as stated in the procurement documents


III.2) Conditions related to the contract

Section IV: Procedure

IV.1) Description

IV.1.1) Type of procedure

Open procedure

IV.1.3) Information about a framework agreement or a dynamic purchasing system

The procurement involves the establishment of a framework agreement with several operators.

Envisaged maximum number of participants to the framework agreement: 10

IV.1.8) Information about Government Procurement Agreement (GPA)

The procurement is covered by the Government Procurement Agreement: Yes

IV.2) Administrative information

IV.2.2) Time limit for receipt of tenders or requests to participate

Date: 08/06/2020

Local time: 12:00

IV.2.4) Languages in which tenders or requests to participate may be submitted

EN

CY

IV.2.6) Minimum time frame during which the tenderer must maintain the tender

Duration in months: 3 (from the date stated for receipt of tender)

IV.2.7) Conditions for opening of tenders

Date: 08/06/2020

Local time: 12:00

Section VI: Complementary information

VI.1) Information about recurrence

This is a recurrent procurement: No

VI.2) Information about electronic workflows

Electronic ordering will be used

Electronic invoicing will be accepted

Electronic payment will be used

VI.3) Additional information

Bidders will need to create an account via In-Tend (https://in-tendhost.co.uk/cardiffuniversity/aspx/Home) in order to view the tender documents.

Under the terms of this contract the successful supplier(s) will be required to deliver Community Benefits in support of the authority’s economic and social objectives. Accordingly, contract performance conditions may relate in particular to social and environmental considerations. The Community Benefits included in this contract are:

As stated within the tender document

(WA Ref:101107)

The buyer considers that this contract is suitable for consortia.

VI.4) Procedures for review

VI.4.1) Review body

High Court

Royal Courts of Justice, The Strand

London

WC2A 2LL

UK

Telephone: +44 2079477501

VI.5) Date of dispatch of this notice

14/04/2020

Coding

Commodity categories

ID Title Parent category
73111000 Research laboratory services Research services

Delivery locations

ID Description
1022 Cardiff and Vale of Glamorgan

Alert region restrictions

The buyer has restricted the alert for this notice to suppliers based in the following regions.

ID Description
There are no alert restrictions for this notice.

Document family

Notice details
Publication date:
15 April 2020
Deadline date:
17 January 2021 00:00
Notice type:
02 Contract Notice
Authority name:
Cardiff University
Publication date:
09 June 2020
Notice type:
14 Corrigendum
Authority name:
Cardiff University
Publication date:
19 January 2021
Notice type:
03 Contract Award Notice - Incomplete Procedure
Authority name:
Cardiff University

About the buyer

Main contact:
Buyline@cardiff.ac.uk
Admin contact:
N/a
Technical contact:
N/a
Other contact:
N/a

Further information

Date Details
04/06/2020 15:24
Notice date(s) changed
IV.2.2) Time limit
Old date: 08/06/2020 12:00
New date: 19/06/2020 17:00

IV.2.7) Conditions for opening of tenders
Old date: 08/06/2020 12:00
New date: 19/06/2020 17:00

Please be advised that the closing date for this tender has been extended to 5pm (BST) on 19 June 2020.

The University has decided to extend the date on the basis that there are still outstanding clarification questions from potential suppliers which the University has not yet been able to respond to. This is due to the capacity issues with the limited number of staff who can respond to such clarification questions.

Please note that only the tender deadline has been extended. The deadline for clarification questions has closed and will remain so.
18/01/2021 21:38
Notice Cancelled
This notice has been cancelled. The original deadline date of 19/06/2020 is no longer applicable.

Change of requirements therefore procurement has been withdrawn from the marketplace

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